Nobel Prize in Chemistry in 2015 – RIA Novosti

Thomas Lindahl (Tomas Lindahl) was born in 1938 in Stockholm, Sweden.

In 1967 he received the degree of Doctor of Philosophy (PhD), in 1970 – Doctor of Medicine Sciences (MD) at the Karolinska Institute in Stockholm, Sweden. After receiving the degree of Doctor of Philosophy he was engaged in research at Princeton University in New Jersey (USA) and The Rockefeller University in New York (USA).

In the years 1978-1982 – Professor of Medical and Physiological Chemistry at the University of Gothenburg (Sweden).

In 1981, he moved to Britain, began working at the Cancer Research Fund (now Cancer Research UK) as Chief Scientist.

In 1984-2007 he was the director of the Clare Hall Laboratories (Laboratory of the Research Institute of Cancer UK (The Cancer Research UK London Research Institute)). Under his leadership, the laboratory has become a leading center for research reparation (restoration) of DNA.

Currently, Tomas Lindahl – the honorary head of the research group at the Institute of the name of Francis Crick (Francis Crick Institute, UK).

Thomas Lindahl is a member of the Swedish and the Norwegian Academy of Sciences, a member of the Royal Society of London.

In 2007, he was awarded the Royal Medal of the Royal Society, in 2010 was awarded the Copley Medal – the highest award of the Royal Society. In 2009 he was awarded the French Institute of Health and Medical Research.

7 October 2015 Thomas Lindahl won the Nobel Prize in Chemistry for the discovery of cellular tools for DNA repair.

Paul Modric (Paul Modrich) was born in 1946.

In 1968, he graduated from the Massachusetts Institute of Technology, a bachelor’s degree, in 1973 received his doctorate at Stanford University (California, USA).

Since 1976 works at the Institute at Duke for Research on Cancer (Duke Cancer Institute), part of the medical school at Duke University (Durham, NC, USA).

Since 1984 – Professor of Biochemistry , since 1988 – professor emeritus of medicine.

Since 1994 – researcher at the Howard Hughes Medical Institute.

Paul Modric – a member of the National Academy of Sciences (1993), a member of the Institute of Medicine of the National Academy of Sciences (2003), the American Academy of Arts and Sciences (2004).

Modric most of his life devoted to the study of how organisms prevent the occurrence of mutations in their genetic material. He first became interested in molecular genetics as a student. While writing the thesis at Stanford, he studied how the enzyme ligase (enzyme glued together two pieces of double-stranded DNA), and showed that affects the viability of the microbe E. coli.

As a result of research Modric found that all living cells contain a special protein system, whose main objective is to fix errors in DNA that occur in it as a result of aggressive compounds, radiation, or “mistakes” during cell division. Such proteins are able to find “gaps” in the chain of DNA, the “wrong” letter-nucleotides, to correct them or to initiate a self-destruct system cells if the error can not be remedied.

7 October 2015 Gender Modric was awarded the Nobel Prize in Chemistry for the discovery of cellular tools for DNA repair.

Aziz Sankar (Aziz Sancar) was born in 1946 in the town of Savur (Turkey).

In 1963, he entered the Medical Faculty of Istanbul University, intending to become a doctor. During training, interested in biochemistry. After graduation he worked for two years to rural doctor.

In 1973, Suncare Aziz entered the department of Molecular Biology, University of Texas at Dallas (USA). The main theme of the study, researchers at the University became the nature of the chromophore photolyase. DNA photolyase – one of the repair enzymes (recovery) DNA, activation of which is under the influence of visible light.

After receiving his doctorate in 1977, Sankar continued to study DNA repair laboratory at Yale University.

In 1982, Suncare became an associate professor of biochemistry University of North Carolina at Chapel Hill (USA) and continued to study photolyase and other DNA repair pathways.

Currently, Aziz Sankar is a professor of Biochemistry and Biophysics, School of Medicine University of North Carolina at Chapel Hill.

A member of the National Academy of Sciences of the USA (2005), the Academy of Sciences of Turkey (2006).

Honorary Visiting Professor of the Chinese Academy of Sciences (2014).

The scientist received numerous awards in recognition of his contribution to science, including a Presidential Young Investigator Award from the National Science Foundation (1984), Award of the National Institutes of Health (NIH) MERIT (1995), the award ” Outstanding graduate “from the University of Texas (2009), and others.

7 October 2015 Aziz Sankara awarded the Nobel Prize in Chemistry in 2015 for his discovery of cellular tools for DNA repair.

The material is based on information RIA Novosti and open source