Scientists have learned how to diagnose a dangerous pathology for pregnant urine – TASS

MOSCOW, 31 May. / TASS /. The team of scientists from the Moscow Institute of Physics and Technology (MIPT) and Moscow’s other research centers have found a way for the analysis of urine to diagnose pre-eclampsia – a serious disease, which affects pregnant women. Scientists have found in the urine of pregnant biomarkers of the disease, according to the press service of the MIPT.

“We were able to confirm the number of markers previously proposed foreign colleagues, and to show some of the new. You can create an effective clinical method on the basis of our development” – listed in the press release, the words of Alexei Kononikhin, deputy head of the laboratory of ion and molecular physics MIPT

How dangerous preeclampsia

Pre-eclampsia -. it is a violation that occurs in the second half of pregnancy, in which at mother increased blood pressure and urine protein levels. In this condition, a woman suffers from headaches, swelling, fainting, and other unpleasant and sometimes dangerous symptoms. Preeclampsia exposes the health and life of the expectant mother and her child at serious risk. Symptoms of disease are ambiguous, so it is difficult to diagnose and prescribe treatment

Protein traces of disease

One of the main symptoms of pre-eclampsia is a marked increase in the concentration of protein in the blood:. From normal (0.03 g / l) to the critical (0.3 g / l and above). To find information about the disease, scientists have used peptides (pieces of protein) that stand out in women with preeclampsia. For a diagnosis of needs analysis of the available biomaterials, ie urine, and there is no need for injections for blood.

In order to identify potential peptides, biomarkers, researchers compared samples of the three groups of patients of the Scientific Center for Obstetrics, Gynecology and Perinatology . Academician VI Kulakov of ten people: a woman with a normal pregnancy, with moderate to severe forms of preeclampsia. As a result, the researchers found 35 peptide biomarker of preeclampsia.

The diagnostic method is based on a urine test will allow in the future accurately identify this pathology and promptly assign the appropriate treatment.

The article with the results of the study, which had a scholars from the Moscow physical-technical Institute, Scientific center for Obstetrics, gynecology and Perinatology named after academician VI Kulakov, the Institute of Biochemical Physics. NM Emanuel Academy of Sciences and the Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences published in the Journal of Proteomics.